Brain
back to body
In a study related to the link between periodontal disease and Alzheimer’s, 98% of subjects were found to have the same oral bacteria known for causing gum disease also located inside of their brains (discoverable by autopsy). The same researchers tested specific bacterial blockers in mice, finding that it reduced “neurodegeneration” in their brains. Similar studies showed that 7 in 10 Alzheimer’s patients had the bacterial DNA inside of their cerebrospinal fluid.
An estimated 5 million Americans have Alzheimer’s disease and it is the most common form of dementia. And over 50% of adults will experience at least some form of gingival infection during their lifetime.
It’s thought that the bacteria known for gingivitis and periodontal disease potentially produce specific toxic proteins that thereby affect the brain. The link between periodontal disease and dementia disorders is one that influences the need to promote better gum health, especially in families with a genetic predisposition to either condition.
The bacteria in this case is Porphyromonas gingivalis, or "p. gingivalis" for short. The toxic proteins secreted by the bacteria are shown to destroy brain neurons in lab studies.
Caught early enough, gingivitis can be reversed before it progresses into periodontal disease. Aggressive periodontal infections can fortunately be intercepted, eliminating spread of bacteria to other parts of the body so that it does not further complicate the overall health — and possible mental performance — of the individual.
Recognizing the signs of early gum disease could be easier for individuals and their caregivers to pinpoint than initial signs of dementia. By promoting better periodontal health from an earlier age, it’s possible to reduce the exposure to toxin-causing bacteria that are known to affect our brains and potential cognitive capabilities.